Ipamorelin (5MG)
$49.99
Shipping Calculated at checkout.
Availability: 157 in stock
Low Stock | Order now
FREE SHIPPING
99%+ PURITY
MADE IN USA
What is Ipamorelin (5MG)?
Ipamorelin is a synthetic pentapeptide classified as a selective growth hormone secretagogue (GHS) that targets the ghrelin receptor (GHS‑R1a) [1][2]. It was developed to trigger growth hormone (GH) release in a highly selective manner, showing minimal stimulation of other pituitary hormones like ACTH, prolactin, or cortisol [2][3].
Chemical Structure of Ipamorelin (5MG)
The peptide sequence is Aib–His–D‑2Nal–D‑Phe–Lys–NH₂, with a chemical formula of C₃₈H₄₉N₉O₅ and molecular weight of ~711.9 Da [1][4].
- Aib (alpha‑aminoisobutyric acid) and 2Nal (2‑naphthylalanine) improve metabolic stability and receptor binding.
- The amidated C-terminal increases resistance to enzymatic degradation.
What Are the Effects of Ipamorelin (5MG)?
Selective GH Release:
Ipamorelin promotes dose-dependent GH secretion without the broad endocrine activation seen with some GHRPs [2][3].
Specificity:
Exhibits minimal effect on ACTH, prolactin, and cortisol, allowing for selective GH-axis studies [2].
Pharmacokinetics:
Human PK studies show a terminal half-life of ~2 hours and GH peak around 0.7 hours post-infusion [3][5].
Metabolic & Regenerative Insights:
Research indicates benefits for cellular regeneration and anabolic pathways in controlled studies [6].
Citations
- PubChem Compound Summary for Ipamorelin (CID 9831659): sequence Aib–His–D‑2Nal–D‑Phe–Lys–NH₂; molecular data.
- Moulin A, Ryan J, Martinez J, Fehrentz JA. “Ipamorelin, the first selective growth hormone secretagogue.” Eur J Endocrinol. 1998;139(5):552–560.
- Gobburu JV, Agersø H, Jusko WJ, Ynddal L. “Pharmacokinetic-pharmacodynamic modeling of ipamorelin in human volunteers.” Pharm Res. 1999;16(9):1412–1418.
- PubChem data confirms the pentapeptide sequence and structural modifications.
- Agersø H, et al. “Pharmacokinetics and pharmacodynamics of ipamorelin, a new GH secretagogue, in humans.” Br J Clin Pharmacol. 2001;52(3):273–279.
- Peptides.guide – Ipamorelin research summary, metabolic and regenerative effects.
Add a review
Ipamorelin (5MG)
Your review
* Review is required
Name
* Name is required
Email
* Email is required
* Please confirm that you are not a robot
| 5 star | 0% | |
| 4 star | 0% | |
| 3 star | 0% | |
| 2 star | 0% | |
| 1 star | 0% |
0 of 0 reviews
Sorry, no reviews match your current selections
