BPC-157 (10MG)

Tissue Regeneration & Wound Healing:

Preclinical studies in rodents report accelerated healing of tendons, ligaments, skin wounds, and muscle injuries, correlating with increased fibroblast growth, collagen synthesis, and angiogenesis [5][6][8].

Gastrointestinal Protection:

Demonstrated anti‑ulcer and cytoprotective effects in gastric injury models, with regulated villus‑crypt structure and intestinal tissue preservation [7].

Angiogenesis & Vascular Repair:

Stimulates vascular endothelial growth factor (VEGF) signaling and nitric oxide pathways, promoting blood vessel formation in ischemic and injury models [4][7][9].

Neuro‑ & Organ‑Protection:

Experimental findings suggest BPC‑157 mitigates brain and nerve injury, maintains liver and kidney integrity under toxic stress, and reduces inflammatory markers [5][11].

Anti‑Inflammatory & Oxidative Stress Reduction:

Modulates nitric oxide and inflammatory cytokines, displaying both antioxidant and analgesic effects in animal research [4][7][11].

Safety Profile:

To date, studies report low toxicity and no significant adverse immunogenic or endocrine reactions under laboratory conditions [5][10].

Citations

1. PubChem, “BPC‑157 Compound Summary,” NC­BI PubChem, CID 9941957.
2. BPC‑157 Peptide, Peptide Sciences, “What is BPC‑157 Peptide?”
3. PubChem, BPC‑157 molecular data (formula, weight).
4. PubChem, physicochemical properties and stability data.
5. S. Seiwerth et al., “Stable Gastric Pentadecapeptide BPC‑157 and Wound Healing,” Front. Pharmacol., 2021, 12:627533.
6. M. Staresinic et al., “Gastric pentadecapeptide BPC‑157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocyte growth,” J Orthop Res., 2003, 21(6):976–983.
7. Chung‑Hsun Chang, W.‑C. Tsai, M.‑S. Lin et al., “The promoting effect of pentadecapeptide BPC‑157 on tendon healing involves tendon outgrowth, cell survival, and cell migration,” J Appl Physiol., 2011, 110(3):774–780.
8. “Stable gastric pentadecapeptide BPC‑157: novel therapy in gastrointestinal tract,” Curr Pharm Des., 2011.
9. BPC‑157 peptide promotes angiogenesis via VEGFR2 and nitric oxide signaling in ischemic models.
10. Peptides.org, “BPC‑157 Reviews, Clinical Trials, and Safety,”
11. T. Cerovecki et al., “Pentadecapeptide BPC‑157 (PL 14736) improves ligament healing in the rat,” J Orthop Res., 2010, 28(9):1155–1161.